2015 Journal of the Formosan Medical Association = Taiwan yi zhi
* Successful treatment of chronic hepatitis B and D with pegylated-interferon plus entecavir.
- Interferon-based regimen has been used to treat hepatitis D virus (HDV) super-infection on top of hepatitis B virus (HBV) carriers; however, viral relapse is frequent after stopping therapy. Recently, quantitative hepatitis B surface antigen (qHBsAg) was introduced to help the management of chronic hepatitis B (CHB). Little is known about its role in the treatment of HBV and HDV dual infection. Herein, we reported a 45-year-old male HBV carrier with HDV co-infection who received combination therapy of pegylated-interferon α-2a plus entecavir. The qHBsAg level was adopted as the treatment guidance and a consolidation therapy of 12 months was continued after HBsAg loss. The patient achieved HBsAg seroconversion with HDV RNA undetectable after 35 months of combination therapy and sustained therapeutic response 12 months post-therapy. Therefore, personalized response-guided therapy by using qHBsAg may be an option for the treatment for HBV and HDV dual infection.
=>1.取り扱い, 扱い, 治療, 待遇, 処理, 処置, 2.台本, シナリオ
Overview of noun treatment
The noun treatment has 4 senses (first 4 from tagged texts)
1. (28) treatment, intervention -- (care provided to improve a situation (especially medical
procedures or applications that are intended to relieve illness or injury))
2. (25) treatment, handling -- (the management of someone or something; "the handling of prisoners";
"the treatment of water sewage"; "the right to equal treatment in the criminal justice system")
3. (4) treatment -- (a manner of dealing with something artistically; "his treatment of space
borrows from Italian architecture")
4. (2) discussion, treatment, discourse -- (an extended communication (often interactive) dealing
with some particular topic; "the book contains an excellent discussion of modal logic"; "his
treatment of the race question is badly biased")
--- WordNet end ---