ELIZA

return kwic search for tumor out of >500 occurrences
305909 occurrences (No.73 in the rank) during 5 years in the PubMed. [no cache] 500 found

114) The diagnostic and predictive abilities of biomarkers are limited by the heterogeneous nature of HCCs; there is no perfect single biomarker of this tumor.

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PMID:24275343 DOI:10.1016/j.cgh.2013.10.038

2015 Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

* Update on biomarkers of hepatocellular carcinoma.

- New biomarkers of hepatocellular carcinoma (HCC) have been identified using advanced genomic, proteomic, and metabolomics technologies. These are being developed not only for use in diagnosis of HCC, but also in prediction of patient and treatment outcomes and individualization of therapy. Some HCC biomarkers are currently used in surveillance to detect early stage HCCs and reduce mortality. Further studies are needed to determine whether the recently identified HCC biomarkers can be used in clinical practice; most are only in phase 1 or 2 studies. The diagnostic and predictive abilities of biomarkers are limited by the heterogeneous nature of HCCs; there is no perfect single biomarker of this tumor. To improve performance, combinations of biomarkers (panels), or combinations of biomarkers and clinical parameters or laboratory test results, might be required. We describe recently discovered biomarkers of HCC and discuss challenges to their development and application.

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[frequency of next (right) word to tumor]

(1)36 cells	(17)6 size	(33)3 lysis	(49)2 progression,
(2)23 suppressor	(18)6 suppression	(34)3 onset	(50)2 recurred
(3)22 progression	(19)6 tissue	(35)3 targeting	(51)2 recurrence
(4)20 necrosis	(20)6 with	(36)3 to	(52)2 regression
(5)19 null	(21)5 angiogenesis	(37)3 types	(53)2 response
(6)17 growth	(22)5 initiating	(38)2 1	(54)2 samples,
(7)15 cell	(23)5 suppressive	(39)2 activity	(55)2 site
(8)14 was	(24)5 volume	(40)2 burden	(56)2 size,
(9)12 and	(25)4 model	(41)2 classification	(57)2 that
(10)11 development	(26)4 sites	(42)2 composed	(58)2 the
(11)11 in	(27)4 suppressors	(43)2 expression	(59)2 tissue,
(12)11 of	(28)3 effects	(44)2 heterogeneity	(60)2 tissues
(13)7 microenvironment	(29)3 excision	(45)2 invasion	(61)2 treatment
(14)6 formation	(30)3 extension	(46)2 is
(15)6 promotion	(31)3 had	(47)2 metastasis
(16)6 samples	(32)3 local	(48)2 mice

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--- WordNet output for tumor --- =>膨らみ, 出っ張り, 腫瘍 Overview of noun tumor The noun tumor has 1 sense (first 1 from tagged texts) 1. (18) tumor, tumour, neoplasm -- (an abnormal new mass of tissue that serves no purpose) --- WordNet end ---