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305909 occurrences (No.73 in the rank) during 5 years in the PubMed. [no cache] 500 found
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305909 occurrences (No.73 in the rank) during 5 years in the PubMed. [no cache] 500 found
| 285) The aim of the present article is to review the available information on ELPs (including our recent investigations), their properties, drug delivery applications to tumor sites and future perspectives. |
| PMID:24215207 DOI:10.3109/10717544.2013.853210 |
| 2015 Drug delivery |
| * Elastin-like polypeptides and their applications in anticancer drug delivery systems: a review. |
| - Elastin-like polypeptides (ELPs) are large molecular weight biopolymers. They have been widely studied as macromolecular carriers for targeted delivery of drugs. The aim of the present article is to review the available information on ELPs (including our recent investigations), their properties, drug delivery applications to tumor sites and future perspectives. This review also provides information on the use of short synthetic ELPs for making ELP-drug conjugates, for targeted delivery of anticancer drugs. In the present review we also focus on the point that short ELPs can also be used for targeting anticancer drugs to tumor sites as they behave similar to long ELPs regarding their capacity to undergo inverse temperature transition (ITT) behavior. |
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(1)36  cells |
(17)6 size |
(33)3 lysis |
(49)2 progression, |
| (2)23 suppressor |
(18)6 suppression |
(34)3 onset |
(50)2 recurred |
| (3)22 progression |
(19)6 tissue |
(35)3 targeting |
(51)2 recurrence |
| (4)20 necrosis |
(20)6 with |
(36)3 to |
(52)2 regression |
| (5)19 *null* | (21)5 angiogenesis |
(37)3 types |
(53)2 response |
| (6)17 growth |
(22)5 initiating |
(38)2 1 |
(54)2 samples, |
| (7)15 cell |
(23)5 suppressive |
(39)2 activity |
(55)2 site |
| (8)14 was |
(24)5 volume |
(40)2 burden |
(56)2 size, |
| (9)12 and |
(25)4 model |
(41)2 classification |
(57)2 that |
| (10)11 development |
(26)4 sites |
(42)2 composed |
(58)2 the |
| (11)11 in |
(27)4 suppressors |
(43)2 expression |
(59)2 tissue, |
| (12)11 of |
(28)3 effects |
(44)2 heterogeneity |
(60)2 tissues |
| (13)7 microenvironment |
(29)3 excision |
(45)2 invasion |
(61)2 treatment |
| (14)6 formation |
(30)3 extension |
(46)2 is |
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| (15)6 promotion |
(31)3 had |
(47)2 metastasis |
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| (16)6 samples |
(32)3 local |
(48)2 mice |
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--- WordNet output for tumor ---