ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
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kwic search for under out of >500 occurrences
321496 occurrences (No.66 in the rank) during 5 years in the PubMed. [cache]
197) While both mEFs and mFMSCs are readily able to reduce TNF-α secretion by LPS/IFN-γ-activated BV-2 microglia, mFMSCs and mEFs display strikingly opposite behavior with regard to VEGF production under normal and inflammatory conditions.
* Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain.
- Although intracerebral transplantation of various fibroblast(-like) cell populations has been shown feasible, little is known about the actual in vivo remodeling of these cellular grafts and their environment. In this study, we aimed to compare the in vitro and in vivo behavior of two phenotypically similar-but developmentally distinct-fibroblast-like cell populations, namely, mouse embryonic fibroblasts (mEFs) and mouse fetal membrane-derived stromal cells (mFMSCs). While both mEFs and mFMSCs are readily able to reduce TNF-α secretion by LPS/IFN-γ-activated BV-2 microglia, mFMSCs and mEFs display strikingly opposite behavior with regard to VEGF production under normal and inflammatory conditions. Whereas mFMSCs downregulate VEGF production upon coculture with LPS/IFN-γ-activated BV-2 microglia, mEFs upregulate VEGF production in the presence of LPS/IFN-γ-activated BV-2 microglia. Subsequently, in vivo grafting of mFMSCs and mEFs revealed no difference in microglial and astroglial responses toward the cellular grafts. However, mFMSC grafts displayed a lower degree of neoangiogenesis compared to mEF grafts, thereby potentially explaining the lower cell number able to survive in mFMSC grafts. In summary, our results suggest that physiological differences between fibroblast-like cell populations might lie at the basis of variations in histopathological and/or clinical outcome following cell grafting in mouse brain.
=>以下の, (治療, 試練, 刑罰)を受けて, 下部の, の下に, ・・の下に
Overview of adj under
The adj under has 2 senses (first 2 from tagged texts)
1. (2) nether, under -- (located below or beneath something else; "nether garments"; "the under
parts of a machine")
2. (1) under -- (lower in rank, power, or authority; "an under secretary")
Overview of adv under
The adv under has 8 senses (first 1 from tagged texts)
1. (2) under -- (down to defeat, death, or ruin; "their competitors went under")
2. under -- (through a range downward; "children six and under will be admitted free")
3. under -- (into unconsciousness; "this will put the patient under")
4. under -- (in or into a state of subordination or subjugation; "we must keep our disappointment
under")
5. under -- (below some quantity or limit; "fifty dollars or under")
6. under -- (below the horizon; "the sun went under")
7. under -- (down below; "get under quickly!")
8. under, below -- (further down; "see under for further discussion")
--- WordNet end ---