ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for used to out of >500 occurrences
298981 occurrences (No.78 in the rank) during 5 years in the PubMed. [cache]
236) The modified Franz-diffusion cell and freshly excised goat corneas were used to test drug corneal permeability.
--- ABSTRACT ---
PMID:24490828 DOI:10.3109/10837450.2014.882935
2015 Pharmaceutical development and technology
* Development and characterization of itraconazole-loaded solid lipid nanoparticles for ocular delivery.
- The purpose of this study was to investigate the feasibility of entrapping water-insoluble drug itraconazole into solid lipid nanoparticles (SLNs) for topical ocular delivery. The drug-loaded SLNs were prepared from stearic acid and palmitic acid using different concentrations of polyvinyl alcohol employed as emulsifier. SLNs were prepared by the melt-emulsion sonication and low temperature-solidification method and characterized for particle size, zeta potential, drug loading and drug entrapment efficiency. The mean particle size of SLNs prepared with stearic acid ranged from 139 to 199 nm, while the SLNs prepared with palmitic acid had particle size in the range of 126-160 nm. The SLNs were spherical in shape. Stearic acid-SLNs showed higher entrapment of drug compared with palmitic acid-SLNs. Differential scanning calorimetry (DSC) and X-ray diffraction measurements showed decrease in crystallinity of drug in the SLN formulations. The modified Franz-diffusion cell and freshly excised goat corneas were used to test drug corneal permeability. Permeation of itraconazole from stearic acid-SLNs was higher than that obtained with palmitic acid-SLNs. The SLNs showed clear zone of inhibition against Aspergillus flavus indicating antimicrobial efficacy of formulations.
--- ABSTRACT END ---
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[frequency of next (right) word to used to]
(1)28 assess (20)5 design (39)3 establish (58)2 find
(2)28 identify (21)5 increase (40)3 observe (59)2 fit
(3)23 evaluate (22)5 inform (41)3 prevent (60)2 form
(4)20 study (23)5 obtain (42)3 solve (61)2 further
(5)17 estimate (24)5 quantify (43)3 validate (62)2 gain
(6)17 measure (25)5 reconstruct (44)2 accurately (63)2 help
(7)16 determine (26)4 calculate (45)2 address (64)2 improve
(8)16 examine (27)4 characterize (46)2 amplify (65)2 make
(9)12 explore (28)4 confirm (47)2 avoid (66)2 match
(10)10 treat (29)4 construct (48)2 be (67)2 optimize
(11)9 analyze (30)4 illustrate (49)2 conduct (68)2 perform
(12)8 develop (31)4 reduce (50)2 create (69)2 prepare
(13)8 investigate (32)4 screen (51)2 demonstrate (70)2 produce
(14)8 predict (33)4 simulate (52)2 derive (71)2 promote
(15)7 collect (34)4 verify (53)2 describe (72)2 recruit
(16)7 compare (35)3 classify (54)2 distinguish (73)2 represent
(17)7 test (36)3 compute (55)2 explain (74)2 select
(18)6 analyse (37)3 control (56)2 extrapolate
(19)6 detect (38)3 define (57)2 facilitate

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--- WordNet output for used --- =>1.〜に慣れて, 2.用いられた, 中古の Overview of verb use The verb use has 6 senses (first 3 from tagged texts) 1. (603) use, utilize, utilise, apply, employ -- (put into service; make work or employ for a particular purpose or for its inherent or natural purpose; "use your head!"; "we only use Spanish at home"; "I can't use this tool"; "Apply a magnetic field here"; "This thinking was applied to many projects"; "How do you utilize this tool?"; "I apply this rule to get good results"; "use the plastic bags to store the food"; "He doesn't know how to use a computer") 2. (12) use, habituate -- (take or consume (regularly or habitually); "She uses drugs rarely") 3. (8) use, expend -- (use up, consume fully; "The legislature expended its time on school questions") 4. use -- (seek or achieve an end by using to one's advantage; "She uses her influential friends to get jobs"; "The president's wife used her good connections") 5. practice, apply, use -- (avail oneself to; "apply a principle"; "practice a religion"; "use care when going down the stairs"; "use your common sense"; "practice non-violent resistance") 6. use -- (habitually do something (use only in the past tense); "She used to call her mother every week but now she calls only occasionally"; "I used to get sick when I ate in that dining hall"; "They used to vacation in the Bahamas") Overview of adj used The adj used has 3 senses (first 3 from tagged texts) 1. (4) used -- (employed in accomplishing something; "the principle of surprise is the most used and misused of all the principles of war"- H.H.Arnold & I.C.Eaker) 2. (1) exploited, ill-used, put-upon, used, victimized, victimised -- (of persons; taken advantage of; "after going out of his way to help his friend get the job he felt not appreciated but used") 3. (1) secondhand, used -- (previously used or owned by another; "bought a secondhand (or used) car") --- WordNet end ---